The global burden of physical inactivity

London, UK – The global effort, undertaken by the Lancet Physical Activity Series Working Group, suggests that physical inactivity is responsible for 6% of the burden of coronary heart disease and 7% of the burden of type 2 diabetes. In addition, the research group notes than one in 10 breast and colon cancers are attributed to a lack of exercise.

Dr Pamela Das, executive editor of the Lancet, said during a press conference announcing the results of the studies,”I think it’s fair to say that physical activity has been a neglected dimension of prevention and intervention worldwide. We all know that physical activity is good for us. We’re told all the time that we should be doing more of it, but today there has been quite a lot more focus —as there should be —on the individual. For a number of reasons, existing approaches to mobilize large segments of the population to do even minimal levels of physical activity are just not working.”

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HRT ups BP; risk of hypertension higher with longer duration of use

Penrith, Australia – A large new study of over 40,000 postmenopausal women has found that use of hormone replacement therapy (HRT) is associated with an increased risk of high blood pressure. The results also show, for the first time, that the risk of hypertension rises with longer duration of HRT use, say Dr Christine L Chiu (University of Western Sydney, Penrith, Australia) and colleagues in PLoS One.

And importantly, “the association between using HRT and high blood pressure was more prominent for younger postmenopausal women, aged 45-55 years,” senior author Dr Joanne M Lind (University of Western Sydney) told heartwire.

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Patients many times more likely to have heart attacks after knee or hip replacement

According to a recent report at, people over age 60 who have surgery to replace a worn-out hip or knee have a significantly higher risk of having a heart attack after their surgeries, a large new study shows.

The study is published in the Archives of Internal Medicine. It reviewed the medical records of more than 95,000 adults in Denmark who had hip or knee replacement surgeries between 1998 and 2008.

Researchers found that one in 200 people who had a hip replacement had a heart attack within six weeks of surgery. The study also found that one in 500 people who had a knee replacement had a heart attack within six weeks of surgery.

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Cardiac arrest survival improving in U.S. hospitals: Study

(Reuters) – More people hospitalized for cardiac arrest are surviving compared with a decade ago, according to a U.S. study, possibly because of changes in hospital treatment and the way bystanders respond when somebody collapses.

The study, which appeared in the journal Circulation, found that in 2008, the death rate among U.S. residents hospitalized after cardiac arrest was just under 58 percent – down from almost 70 percent in 2001.

Researchers, led by Alejandro Rabinstein of the Mayo Clinic in Rochester, Minnesota, based their findings on a national hospital discharge database that included nearly 1.2 million people hospitalized for cardiac arrest.

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Aging heart cells rejuvenated by modified stem cells

NEW ORLEANS — Damaged and aged heart tissue of older heart failure patients was rejuvenated by stem cells modified by scientists, according to research presented at the American Heart Association’s Basic Cardiovascular Sciences 2012 Scientific Sessions.

The study is simultaneously published in the Journal of the American College of Cardiology.

The research could one day lead to new treatments for heart failure patients, researchers said.

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